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Current issue   Ukr. J. Phys. 2014, Vol. 58, N 6, p.554-561


Perepelytsya S.M., Volkov S.N.

Bogolyubov Institute for Theoretical Physics, Nat. Acad. of Sci. of Ukraine
(14b, Metrolohichna Str., Kyiv 03680, Ukraine; e-mail: perepelytsya@bitp.kiev.ua; snvolkov@bitp.kiev.ua)

Dynamics of Ion-Phosphate Lattice of DNA in Left-Handed Double Helix Form

Section: Soft matter
Original Author's Text: English

Abstract: The conformational vibrations of Z-DNA with counterions are studied in the framework of a phenomenological model developed. The structure of a left-handed double helix with counterions neutralizing the negatively charged phosphate groups of DNA is considered as an ion-phosphate lattice. The frequencies and the Raman intensities for the modes of Z-DNA with Na+ and Mg2+ ions are calculated, and the low-frequency Raman spectra are built. At the spectral interval about the frequency 150 cm−1, a new mode of ion-phosphate vibrations, which characterizes the vibrations of Mg2+ counterions, is found. The results of our calculations show that the intensities of Z-DNA modes are sensitive to the concentration of magnesium counterions. The obtained results describe well the experimental Raman spectra of Z-DNA.

Key words: left-handed double helix, ion-phosphate lattice, DNA.