0372-400Х (Edition in Ukrainian)
2071-0186 (Edition in English)
2071-0194 (in electronic form)
Abbreviated key title: Ukr. J. Phys.
Current issue Ukr. J. Phys. 2014, Vol. 58, N 6, p.554-561
Perepelytsya S.M., Volkov S.N.
Dynamics of Ion-Phosphate Lattice of DNA in Left-Handed Double Helix Form
Section: Soft matter
Original Author's Text: English
Abstract: The conformational vibrations of Z-DNA with counterions are studied in the framework of a phenomenological model developed. The structure of a left-handed double helix with counterions neutralizing the negatively charged phosphate groups of DNA is considered as an ion-phosphate lattice. The frequencies and the Raman intensities for the modes of Z-DNA with Na+ and Mg2+ ions are calculated, and the low-frequency Raman spectra are built. At the spectral interval about the frequency 150 cm−1, a new mode of ion-phosphate vibrations, which characterizes the vibrations of Mg2+ counterions, is found. The results of our calculations show that the intensities of Z-DNA modes are sensitive to the concentration of magnesium counterions. The obtained results describe well the experimental Raman spectra of Z-DNA.
Key words: left-handed double helix, ion-phosphate lattice, DNA.